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Article

Susceptibility to visceral leishmaniasis in the domestic dog is associated with MHC class II polymorphism.

Immunogenetics - 1 Apr 2003

Quinnell Rupert J, Kennedy Lorna J, Barnes Annette, Courtenay Orin, Dye Christopher, Garcez Lourdes M, Shaw Marie-Anne, Carter Stuart D, Thomson Wendy, Ollier William E R

Abstract excerpt

Zoonotic visceral leishmaniasis (VL) is a disease of dogs, humans and other animals caused by the intracellular macrophage parasite Leishmania infantum. We examined the relationship between DLA class II alleles ( DRB1, DQA1, DQB1) and the course of infection in a cohort of Brazilian mongrel dogs exposed to natural L. infantum infection. DLA alleles were typed by sequence-based typing. DLA-DRB1 genotype was...

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Source

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PMID: 12715244
DOI: 10.1007/s00251-003-0545-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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