Article
Pretumor progression: clonal evolution of human stem cell populations.
The American journal of pathology - 1 Apr 2004
Calabrese Peter, Tavaré Simon, Shibata Darryl
Abstract excerpt
Multistep carcinogenesis through sequential cycles of mutation and clonal succession is usually described as tumor progression, or the clonal evolution of tumor cell populations. However, many mutations found in cancers are also compatible with normal appearing phenotypes and therefore genetic pr...
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