Article
Low frequency of FLT3 gene internal tandem duplication and activating loop mutation in therapy-related acute myelocyticleukemia and myelodysplastic syndrome.
Cancer genetics and cytogenetics - 1 Mar 2004
Au Wing Y, Fung Alvin T, Ma Edmond S, Liang Raymond H, Kwong Yok L
Abstract excerpt
FLT3 gene internal tandem duplication (ITD) and activating loop mutations (D835) were determined in 22 cases of therapy-related acute myelocytic leukemia/myelodysplastic syndrome (t-AML/MDS) and 102 cases of de novo AML/MDS. In t-AML/MDS, FLT3 ITD was absent, and D835 was found in only one case o...
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