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Article

A quantitative and immunohistochemical study on apolipoprotein E in brain tissue in Alzheimer's disease.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Hesse C, Bogdanovic N, Davidsson P, Blennow K

Abstract excerpt

Apoliprotein E (ApoE) has been implicated in the pathogenesis of Alzheimer's disease (AD). Antibodies to ApoE label senile plaques (SP), and an interaction between ApoE and beta-amyloid has been found in in vitro studies. Further, an increased frequency of the ApoE epsilon4 allele in AD has been reported in numerous papers. However, the pathogenetic mechanism of ApoE in AD is not known. We studied ApoE in brain...

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Source

Identifiers

PMID: 10559559
DOI: 10.1159/000017189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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