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Article

TGFbeta1, back to the future: revisiting its role as a transforming growth factor.

Cancer biology & therapy - 1 Mar 2004

Glick Adam B

Abstract excerpt

TGFbeta1 was initially identified in culture media from transformed cells as part of a factor that could produce a transformed phenotype in a nontransformed cell line. Subsequently this activity was separated into TGFbeta and TGFalpha an EGF receptor ligand. With the discovery that TGFbeta1 was a potent growth inhibitor of epithelial cells, and the identification of inactivating mutations within the TGFbeta1...

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Source

Identifiers

PMID: 15034302
DOI: 10.4161/cbt.3.3.849

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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