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Article

Cycling without the cyclosome: modeling a yeast strain lacking the APC.

Cell cycle (Georgetown, Tex.) - 1 May 2004

Thornton Brian R, Chen Katherine C, Cross Frederick R, Tyson John J, Toczyski David P

Abstract excerpt

The construction of viable Saccharomyces cerevisiae strains that lack the anaphase promoting complex (APC) was recently reported. The normally lethal deletions of APC genes were suppressed by the double deletion of the PDS1 and CLB5 genes in conjunction with the insertion of multiple copies of th...

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PMID: 15034296

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15034296-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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