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Article

Testing a mathematical model of the yeast cell cycle.

Molecular biology of the cell - 1 Jan 2002

Cross Frederick R, Archambault Vincent, Miller Mary, Klovstad Martha

Abstract excerpt

We derived novel, testable predictions from a mathematical model of the budding yeast cell cycle. A key qualitative prediction of bistability was confirmed in a strain simultaneously lacking cdc14 and G1 cyclins. The model correctly predicted quantitative dependence of cell size on gene dosage of the G1 cyclin CLN3, but it incorrectly predicted strong genetic interactions between G1 cyclins and the...

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Source

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Identifiers

PMID: 11809822
DOI: 10.1091/mbc.01-05-0265
PMCID: PMC65072

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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