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Article

Control analysis of the eukaryotic cell cycle using gene copy-number series in yeast tetraploids.

BMC genomics - 31 Oct 2013

Alcasabas Annette A, de Clare Michaela, Pir Pınar, Oliver Stephen G

Abstract excerpt

BACKGROUND: In the model eukaryote, Saccharomyces cerevisiae, previous experiments have identified those genes that exert the most significant control over cell growth rate. These genes are termed HFC for high flux control. Such genes are overrepresented within pathways controlling the mitotic cell cycle. RESULTS: We postulated that the increase/decrease in growth rate is due to a change in the rate of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24176122
DOI: 10.1186/1471-2164-14-744
PMCID: PMC3826841

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