Article
Histochemical features of stress-induced aggregates in alpha-synuclein overexpressing cells.
Brain research - 9 Apr 2004
Matsuzaki Michiko, Hasegawa Takafumi, Takeda Atsushi, Kikuchi Akio, Furukawa Katsutoshi, Kato Yoji, Itoyama Yasuto
Abstract excerpt
alpha-Synuclein is a major component of intracytoplasmic inclusions including Lewy bodies (LB), Lewy neurites (LN) and glial cytoplasmic inclusions, and plays a key role in neurodegenerative processes in Parkinson's disease (PD) and other synucleinopathies. Although the molecular mechanisms of the disease process still remain to be elucidated, recent studies have suggested that an interaction between reactive...
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