Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Demonstration of a role for α-synuclein as a functional microtubule-associated protein

24 Aug 2004

Abstract excerpt

Alpha-synuclein is a major constituent of pathological intracellular inclusion bodies, a common feature of several neurodegenerative diseases. Two missense mutations in the alpha-synuclein gene have been identified in confirmed autosomal-dominant familial Parkinson's disease, which segregate with the illness. However, the physiological function of alpha-synuclein remains unknown. After biochemical investigations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Nerve injury and regeneration
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15345814
DOI: 10.3233/jad-2004-6412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Demonstration of a role for α-synuclein as a functional microtubule-associated proteinPMID 15345814Read ↗

Alpha-synuclein: its biological function and role in neurodegenerative diseases.Semantic proximity Read ↗

Cross-talk between α-synuclein and the microtubule cytoskeleton in neurodegenerationSemantic proximity Read ↗

Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies.Semantic proximity Read ↗

Parkinsons Disease and other α-SynucleinopathiesSemantic proximity Read ↗

The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases.Semantic proximity Read ↗

Alpha-synuclein dysfunction in Lewy body diseases.Semantic proximity Read ↗

Neuronal microtubules and proteins linked to Parkinson’s disease: a relevant interaction?Semantic proximity Read ↗

Neurodegeneration and the ordered assembly of α-synucleinSemantic proximity Read ↗

Impairment of microtubule‐dependent trafficking by overexpression of α‐synucleinSemantic proximity Read ↗

Nuclear Localization of α-Synuclein and Its Interaction with HistonesSemantic proximity Read ↗

The α‐Synucleinopathies: Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System AtrophySemantic proximity Read ↗

SynucleinopathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.