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Article

Structural determinants of PLD2 inhibition by alpha-synuclein.

Journal of molecular biology - 2 Apr 2004

Payton Jacqueline E, Perrin Richard J, Woods Wendy S, George Julia M

Abstract excerpt

The presynaptic protein alpha-synuclein has been implicated in both neuronal plasticity and neurodegenerative disease, but its normal function remains unclear. We described the induction of an amphipathic alpha-helix at the N terminus (exons 2-4) of alpha-synuclein upon exposure to phospholipid v...

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Source

Identifiers

PMID: 15033366
DOI: 10.1016/j.jmb.2004.02.014

Genes

PLD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15033366-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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