Article
The PS2 integrin ligand tiggrin is required for proper muscle function in Drosophila.
Development (Cambridge, England) - 1 May 1998
Bunch T A, Graner M W, Fessler L I, Fessler J H, Schneider K D, Kerschen A, Choy L P, Burgess B W, Brower D L
Abstract excerpt
Tiggrin is a novel extracellular matrix ligand for the Drosophila PS2 integrins. We have used flanking P elements to generate a precise deletion of tiggrin. Most flies lacking tiggrin die as larvae or pupae. A few adults do emerge and these appear to be relatively normal, displaying only misshapen abdomens and a low frequency of wing defects. Examination of larvae shows that muscle connections, function and...
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