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Article

Control of gene expression by a natural metabolite-responsive ribozyme.

Nature - 18 Mar 2004

Winkler Wade C, Nahvi Ali, Roth Adam, Collins Jennifer A, Breaker Ronald R

Abstract excerpt

Most biological catalysts are made of protein; however, eight classes of natural ribozymes have been discovered that catalyse fundamental biochemical reactions. The central functions of ribozymes in modern organisms support the hypothesis that life passed through an 'RNA world' before the emergence of proteins and DNA. We have identified a new class of ribozymes that cleaves the messenger RNA of the glmS gene in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15029187
DOI: 10.1038/nature02362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Control of gene expression by a natural metabolite-responsive ribozyme.PMID 15029187Read ↗

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