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Article

A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus.

Journal of bacteriology - 1 Apr 2004

Kato Jun-ya, Miyahisa Ikuo, Mashiko Mari, Ohnishi Yasuo, Horinouchi Sueharu

Abstract excerpt

In the model of the A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) regulatory cascade in Streptomyces griseus, A-factor binds ArpA, the A-factor receptor protein, that has bound to the adpA promoter and dissociates it from the DNA, thus inducing the transcription of adpA. AdpA switches on the transcription of a number of genes required for secondary metabolism and morphological differentiation,...

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Identifiers

PMID: 15028707
DOI: 10.1128/JB.186.7.2206-2211.2004
PMCID: PMC374422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus.PMID 15028707Read ↗

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