Article
Transcriptional control by A-factor of two trypsin genes in Streptomyces griseus.
Journal of bacteriology - 1 Jan 2005
Kato Jun-Ya, Chi Won-Jae, Ohnishi Yasuo, Hong Soon-Kwang, Horinouchi Sueharu
Abstract excerpt
AdpA is the key transcriptional activator for a number of genes of various functions in the A-factor regulatory cascade in Streptomyces griseus, forming an AdpA regulon. Trypsin-like activity was detected at a late stage of growth in the wild-type strain but not in an A-factor-deficient mutant. Consistent with these observations, two trypsin genes, sprT and sprU, in S. griseus were found to be members of the AdpA...
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