Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus.

Journal of bacteriology - 1 Aug 2005

Tomono Ayami, Tsai Yisan, Yamazaki Haruka, Ohnishi Yasuo, Horinouchi Sueharu

Abstract excerpt

A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) triggers streptomycin production by inducing the transcription of strR, encoding the pathway-specific transcriptional activator, through signal transduction in the A-factor regulatory cascade in Streptomyces griseus. AdpA, one of the key transcriptional activators in the cascade, bound two upstream activation sites, approximately at nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 4-Butyrolactone
Share to Deoxyribonuclease I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Footprinting

Share to Gene Expression Regulation, Bacterial

Share to Multigene Family

Share to Streptomycin

Share to Trans-Activators

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 16077104
DOI: 10.1128/JB.187.16.5595-5604.2005
PMCID: PMC1196073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus.PMID 16077104Read ↗

Transcriptional switch on of ssgA by A-factor, which is essential for spore septum formation in Streptomyces griseus.Semantic proximity Read ↗

amfR, an essential gene for aerial mycelium formation, is a member of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus.Semantic proximity Read ↗

Autorepression of AdpA of the AraC/XylS family, a key transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus.Semantic proximity Read ↗

Detection of an A-factor-responsive protein that binds to the upstream activation sequence of strR, a regulatory gene for streptomycin biosynthesis in Streptomyces griseusSemantic proximity Read ↗

Transcriptional control by A-factor of two trypsin genes in Streptomyces griseus.Semantic proximity Read ↗

The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis in Streptomyces ansochromogenes.Semantic proximity Read ↗

Control by A-factor of a metalloendopeptidase gene involved in aerial mycelium formation in Streptomyces griseus.Semantic proximity Read ↗

A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus.Semantic proximity Read ↗

Transcriptional Regulator DasR Represses Daptomycin Production through Both Direct and Cascade Mechanisms in Streptomyces roseosporusSemantic proximity Read ↗

Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor.Semantic proximity Read ↗

AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensisSemantic proximity Read ↗

BldD, a master developmental repressor, activates antibiotic production in two Streptomyces speciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.