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Article

Transcriptional switch on of ssgA by A-factor, which is essential for spore septum formation in Streptomyces griseus.

Journal of bacteriology - 1 Feb 2003

Yamazaki Haruka, Ohnishi Yasuo, Horinouchi Sueharu

Abstract excerpt

A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) triggers morphological development and secondary metabolism in Streptomyces griseus. A transcriptional activator (AdpA) in the A-factor regulatory cascade switches on a number of genes required for both processes. AdBS11 was identified in a library of the DNA fragments that are bound by AdpA and mapped upstream of ssgA, which is essential for septum...

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Identifiers

PMID: 12562798
DOI: 10.1128/JB.185.4.1273-1283.2003
PMCID: PMC142869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transcriptional switch on of ssgA by A-factor, which is essential for spore septum formation in Streptomyces griseus.PMID 12562798Read ↗

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