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Article

Modular structure of the human lamin B2 replicator.

Molecular and cellular biology - 1 Apr 2004

Paixão Sónia, Colaluca Ivan N, Cubells Matthieu, Peverali Fiorenzo A, Destro Annarita, Giadrossi Sara, Giacca Mauro, Falaschi Arturo, Riva Silvano, Biamonti Giuseppe

Abstract excerpt

The cis-acting elements necessary for the activity of DNA replication origins in metazoan cells are still poorly understood. Here we report a thorough characterization of the DNA sequence requirements of the origin associated with the human lamin B2 gene. A 1.2-kb DNA segment, comprising the start site of DNA replication and located within a large protein-bound region, as well as a CpG island, displays origin...

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Identifiers

PMID: 15024083
DOI: 10.1128/MCB.24.7.2958-2967.2004
PMCID: PMC371099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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