Article
Extracellular matrix-induced cyclooxygenase-2 regulates macrophage proteinase expression.
The Journal of biological chemistry - 21 May 2004
Khan K M Faisal, Howe Louise R, Falcone Domenick J
Abstract excerpt
Chronic inflammatory diseases are characterized by the persistent presence of macrophages and other mononuclear cells, tissue destruction, cell proliferation, and the deposition of extracellular matrix (ECM). The tissue degradation is mediated, in part, by enhanced proteinase expression by macrop...
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