Article
Exogenous IL-6 inhibits acute inflammatory responses and prevents ischemia/reperfusion injury after intestinal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Apr 2004
Kimizuka Kei, Nakao Atsunori, Nalesnik Michael A, Demetris Anthony J, Uchiyama Takashi, Ruppert Kris, Fink Mitchell P, Stolz Donna B, Murase Noriko
Abstract excerpt
Interleukin-6 (IL-6) is a pleiotropic acute reactant cytokine involved in inflammatory responses. To explore the role of IL-6 in inflammation, this study examined the efficacy of exogenous IL-6 in preventing intestinal ischemia/reperfusion (I/R) injury associated with small bowel transplantation...
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