Article
Effect of CXCR3/HO-1 genes modified bone marrow mesenchymal stem cells on small bowel transplant rejection.
World journal of gastroenterology - 14 Jun 2017
Yin Ming-Li, Song Hong-Li, Yang Yang, Zheng Wei-Ping, Liu Tao, Shen Zhong-Yang
Abstract excerpt
AIM: To investigate whether bone marrow mesenchymal stem cells (BMMSCs) modified with the HO-1 and CXCR3 genes can augment the inhibitory effect of BMMSCs on small bowel transplant rejection. METHODS: Lewis rat BMMSCs were cultured in vitro. Third-passage BMMSCs were transduced with the CXCR3/HO-1 genes or the HO-1 gene alone. The rats were divided into six groups and rats in the experimental group were...
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