Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between the TNFRII 196R allele and diagnosis of rheumatoid arthritis.

Arthritis research & therapy - 1 Jan 2005

Goëb Vincent, Dieudé Philippe, Vittecoq Olivier, Mejjad Othmane, Ménard Jean-François, Thomas Marlène, Gilbert Danièle, Boumier Patrick, Pouplin Sophie, Daragon Alain, Fardellone Patrice, Tron François, Cornélis François, Le Loët Xavier

Abstract excerpt

Tumour necrosis factor (TNF)-alpha plays a key role in the pathogenesis of rheumatoid arthritis (RA). It binds to two receptors, namely TNF receptor (TNFR)I and TNFRII. Several studies have suggested an association between TNFRII 196R/R genotype and RA. The objective of the present study was to evaluate the predictive value of the TNFRII 196R allele for RA diagnosis and prognosis in a cohort of patients with very...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antirheumatic Agents
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Autoimmune Diseases

Share to HLA-DR Antigens

Share to Predictive Value of Tests

Share to Radiography

Share to Receptors, Tumor Necrosis Factor, Type II

Source

Open in PubMed Open full text

Identifiers

PMID: 16207322
DOI: 10.1186/ar1777
PMCID: PMC1257430

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between the TNFRII 196R allele and diagnosis of rheumatoid arthritis.PMID 16207322Read ↗

Tumor necrosis factor receptor II gene polymorphism and severity of rheumatoid arthritis.Semantic proximity Read ↗

Contribution of PTPN22 1858T, TNFRII 196R and HLA-shared epitope alleles with rheumatoid factor and anti-citrullinated protein antibodies to very early rheumatoid arthritis diagnosis.Semantic proximity Read ↗

Association of tumor necrosis factor alpha and its receptor polymorphisms with rheumatoid arthritis in female patients.Semantic proximity Read ↗

Associations between functional TNFR2 196 M/R polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in CaucasiansSemantic proximity Read ↗

Tumor necrosis factor receptor II (TNFRII) exon 6 polymorphism in systemic lupus erythematosus.Semantic proximity Read ↗

The -383A>C TNFRI polymorphism is associated with soluble levels and clinical activity in rheumatoid arthritis.Semantic proximity Read ↗

Association between tumor necrosis factor receptor II and familial, but not sporadic, rheumatoid arthritis: evidence for genetic heterogeneity.Semantic proximity Read ↗

A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy - results from a Swedish cohort study.Semantic proximity Read ↗

Does the age of onset of rheumatoid arthritis influence phenotype?: a prospective study of outcome and prognostic factors.Semantic proximity Read ↗

Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis.Semantic proximity Read ↗

No association of polymorphisms in the tumor necrosis factor receptor I and receptor II genes with disease severity in rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.