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Article

Structural and catalytic diversity in the two family 11 aldo-keto reductases.

Journal of molecular biology - 26 Mar 2004

Ehrensberger Andreas H, Wilson David K

Abstract excerpt

Aldo-keto reductases (AKRs) are a large superfamily of NAD(P)H-dependent enzymes that function in a wide range of biological processes. The structures of two enzymes from the previously uncharacterized family 11 (AKR11A and AKR11B), the products of the iolS and yhdN genes of Bacillus subtilis have been determined. AKR11B appears to be a relatively conventional member of the superfamily with respect to structural...

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Identifiers

PMID: 15019785
DOI: 10.1016/j.jmb.2004.01.059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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