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Article

Structural dynamics in the active site of murine neuroglobin and its effects on ligand binding.

The Journal of biological chemistry - 28 May 2004

Nienhaus Karin, Kriegl Jan M, Nienhaus G Ulrich

Abstract excerpt

We have examined the effects of active site residues on ligand binding to the heme iron of mouse neuroglobin using steady-state and time-resolved visible spectroscopy. Absorption spectra of the native protein, mutants H64L and K67L and double mutant H64L/K67L were recorded for the ferric and ferrous states over a wide pH range (pH 4-11), which allowed us to identify a number of different species with different...

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Identifiers

PMID: 15016813
DOI: 10.1074/jbc.M401561200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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