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Article

The matrix metalloproteinase-21 gene 572C/T polymorphism and the risk of breast cancer.

Anticancer research - 1 Jan 2000

Shagisultanova Elena I, Novikova Inna A, Sidorenko Yuri S, Marchenko George N, Strongin Alex Y, Malkhosyan Sergei R

Abstract excerpt

BACKGROUND: Matrix metalloproteinases (MMPs) contribute in multiple ways to all stages of tumor development, and a number of DNA polymorphisms in the MMP genes are associated with an increased risk of cancer. We previously identified the MMP-21 gene 572C/T polymorphism leading to Ala191Val substitution within the enzyme's catalytic domain. We performed a case-control study to test association between this...

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PMID: 15015597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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