Article
The E-selectin S128R polymorphism is not a risk factor for coronary artery disease in patients with diabetes mellitus type 2.
Thrombosis research - 1 Jan 2003
Endler Georg, Exner Markus, Raith Marianne, Marculescu Rodrig, Mannhalter Christine, Endler Lukas, Wojta Johann, Huber Kurt, Wagner Oswald F
Abstract excerpt
AIM/HYPOTHESIS: E-selectin is thought to play a key role in the early stages of vascular disease by facilitating the attachment of leukocytes to the endothelium. Recently, a polymorphism in the E-selectin gene (S128R) has been associated with higher E-selectin levels in patients with diabetes mellitus and with premature coronary artery disease. The impact of the S128R polymorphism on the development of diabetic...
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