Article
The interactive role of type 2 diabetes mellitus and E-selectin S128R mutation on susceptibility to coronary heart disease.
BMC medical genetics - 20 Jun 2007
Abu-Amero Khaled K, Al-Mohanna Futwan, Al-Boudari Olayan M, Mohamed Gamal H, Dzimiri Nduna
Abstract excerpt
BACKGROUND: The role of gene-environment interactions as risk factors for coronary heart disease (CAD) remains largely undefined. Such interactions may involve gene mutations and disease conditions such as type 2 diabetes mellitus (DM2) predisposing individuals to acquiring the disease. METHODS: In the present study, we assessed the possible interactive effect of DM2 and E-selectin S128R polymorphism with respect...
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