Article
Structure-function analysis of the cysteine string protein in Drosophila: cysteine string, linker and C terminus.
The Journal of experimental biology - 1 Mar 2004
Arnold Christine, Reisch Natascha, Leibold Christian, Becker Sonja, Prüfert Kristina, Sautter Kerstin, Palm Dieter, Jatzke Susanne, Buchner Sigrid, Buchner Erich
Abstract excerpt
Cysteine string proteins (CSPs) are conserved secretory vesicle proteins involved in regulating neurotransmitter and peptide release. While the function of the J-domain has been studied in detail, little is known about other conserved regions. We have constructed mutant genes coding for proteins with modified cysteine string, linker region or C terminus and transformed them into Csp null-mutant Drosophila: In the...
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