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Article

Wide distribution of the cysteine string proteins in Drosophila tissues revealed by targeted mutagenesis.

Cell and tissue research - 1 Nov 1998

Eberle K K, Zinsmaier K E, Buchner S, Gruhn M, Jenni M, Arnold C, Leibold C, Reisch D, Walter N, Hafen E, Hofbauer A, Pflugfelder G O, Buchner E

Abstract excerpt

The "cysteine string protein" (CSP) genes of higher eukaryotes code for a novel family of proteins characterized by a "J" domain and an unusual cysteine-rich region. Previous studies had localized the proteins in neuropil and synaptic terminals of larval and adult Drosophila and linked the temperature-sensitive paralysis of the mutants described here to conditional failure of synaptic transmission. We now use the...

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PMID: 9799436
DOI: 10.1007/s004410051170

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