Article
Manipulation of Alternative Splicing by a Newly Developed Inhibitor of Clks
28 May 2004
Abstract excerpt
The regulation of splice site usage provides a versatile mechanism for controlling gene expression and for the generation of proteome diversity, playing an essential role in many biological processes. The importance of alternative splicing is further illustrated by the increasing number of human diseases that have been attributed to mis-splicing events. Appropriate spatial and temporal generation of splicing...
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