Article
Factors affecting the susceptibility of the mouse pituitary gland to CD8 T-cell-mediated autoimmunity.
Immunology - 1 Mar 2004
De Jersey James, Carmignac Danielle, Le Tissier Paul, Barthlott Thomas, Robinson Iain, Stockinger Brigitta
Abstract excerpt
We have previously shown, in a transgenic mouse model, that the pituitary gland is susceptible to CD8 T-cell-mediated autoimmunity, triggered by a cell-specific model autoantigen, resulting in pan-anterior pituitary hypophysitis and dwarfism. In the present study, we now demonstrate that antigen...
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