Article
HIV type 1 genotypic resistance in a clinical database correlates with antiretroviral utilization.
AIDS research and human retroviruses - 1 Jan 2004
Kagan Ron, Winters Mark, Merigan Thomas, Heseltine Peter
Abstract excerpt
We established a database of HIV-1 reverse transcriptase (RT) and protease (PR) sequences and mutations to monitor the prevalence of antiretroviral drug resistance and mutational patterns in clinical samples submitted for testing to a major U.S. reference laboratory. At the end of 1998, 80% of th...
Topics
- Anti-HIV Agents
- Databases, Genetic
- Drug Resistance, Viral
- Drug Therapy, Combination
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Mutation
- Practice Patterns, Physicians'