Article
Prevalence of antiretroviral drug resistance and resistance-associated mutations in antiretroviral therapy-naïve HIV-infected individuals from 40 United States cities.
HIV clinical trials - 1 Jan 2000
Ross Lisa, Lim Michael L, Liao Qiming, Wine Brian, Rodriguez Allan E, Weinberg Winkler, Shaefer Mark
Abstract excerpt
BACKGROUND: Transmission of drug-resistant HIV strains to antiretroviral therapy (ART)-naïve subjects can negatively impact therapy response. As treatment strategies and utilization of antiretroviral drugs evolve, patterns of transmitted mutations may shift. METHOD: Paired genotypic and phenotypic susceptibility data were retrospectively analyzed for 317 ART-naïve, HIV-infected subjects from 40 small and major...
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