Article
Prevalence of genotypic and phenotypic resistance to anti-retroviral drugs in a cohort of therapy-naïve HIV-1 infected US military personnel.
AIDS (London, England) - 26 May 2000
Wegner S A, Brodine S K, Mascola J R, Tasker S A, Shaffer R A, Starkey M J, Barile A, Martin G J, Aronson N, Emmons W W, Stephan K, Bloor S, Vingerhoets J, Hertogs K, Larder B
Abstract excerpt
OBJECTIVE: While transmission of drug-resistant HIV-1 has been reported, estimates of prevalence of resistance in drug-naïve populations are incomplete. We investigated the prevalence of genotypic mutations and phenotypic antiretroviral resistance in a cohort of HIV-1 infected U.S. military personnel prior to the institution of antiretroviral therapy. DESIGN: Cross-sectional cohort study. METHODS: Plasma was...
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