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Article

Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects.

Toxicology and applied pharmacology - 1 Mar 2004

Xu Mian, Floyd Heather S, Greth Suzanne M, Chang Wen-Chi L, Lohman Kurt, Stoyanova Radka, Kucera Gregory L, Kute Tim E, Willingham Mark C, Miller Mark Steven

Abstract excerpt

Perillyl alcohol (POH) is currently being tested in clinical trials as an anticancer agent, though its mechanism of action has not been definitively established. We treated two human lung cancer cell lines, H322 and H838, with POH to determine its antitumor properties. A sulforhodamine B (SRB) cell proliferation assay was used to determine the effects of POH after 1 and 5 days of treatment with 0.25, 0.5, 0.75,...

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Identifiers

PMID: 14998688
DOI: 10.1016/j.taap.2003.11.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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