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Article

Effects of phospholemman expression on swelling-activated ion currents and volume regulation in embryonic kidney cells.

Neurochemical research - 1 Jan 2004

Davis Cristina E, Patel Manoj K, Miller James R, John J Edward, Jones Larry R, Tucker Amy L, Mounsey J Paul, Moorman J Randall

Abstract excerpt

Phospholemman (PLM) is a 72-amino-acid phosphoprotein that is a major substrate for cAMP-dependent protein kinase, protein kinase C, and NIMA kinase. In lipid bilayers, PLM forms ion channels selective for Cl-, K+, and taurine. Effluxes of these abundant intracellular osmolytes play an important role in the control of dynamic cell volume changes in many cell types. We measured swelling-activated ion currents and...

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Identifiers

PMID: 14992277
DOI: 10.1023/b:nere.0000010447.24128.ac

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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