Article
Cell volume-sensitive chloride channels: phenotypic properties and molecular identity.
Contributions to nephrology - 1 Jan 2006
Okada Yasunobu
Abstract excerpt
Cell volume regulation is essential for the survival of cells. After osmotic swelling, animal cells show a regulatory volume decrease by releasing intracellular K(+), Cl (-)and water. In most cell types, volume-regulatory Cl(-) efflux is induced by activation of electroconductive anion pathways. Among these volume-activated Cl(-) channels, the most important and specific is a volume-sensitive outwardly rectifying...
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