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Article

Second eigenvalue of the Laplacian matrix for predicting RNA conformational switch by mutation.

Bioinformatics (Oxford, England) - 12 Aug 2004

Barash Danny

Abstract excerpt

MOTIVATION: Conformational switching in RNAs is thought to be of fundamental importance in several biological processes, including translational regulation, regulation of self-cleavage in viruses, protein biosynthesis and mRNA splicing. Current methods for detecting bi-stable RNAs that can lead to structural switching when triggered by an outside event rely on kinetics, energetics and properties of the...

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PMID: 14988109
DOI: 10.1093/bioinformatics/bth157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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