Article
Molecular targets for therapy of hepatitis B virus-induced hepatocellular carcinoma.
Minerva gastroenterologica e dietologica - 1 Dec 2006
Tharayil V S, Roberts L R
Abstract excerpt
Chronic hepatitis B virus (HBV) infection is the most frequent risk factor for development of hepatocellular carcinoma (HCC) worldwide. Studies of the molecular genetics and pathophysiology of HCC suggest that there are significant differences in the allelic imbalance, genome copy number, and gen...
Topics
- Aflatoxins
- Alleles
- Apoptosis
- Carcinoma, Hepatocellular
- Cell Cycle
- DNA, Viral
- Gene Expression
- Genes, Viral
- Genetic Therapy
- Genomic Instability
- Genotype
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Liver Neoplasms
- Phenotype
- Risk Factors
- Virus Integration
