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Article

Role of interstitial collagenase gene promoter polymorphism in the etiology of gastric cancer.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association - 1 Jan 2000

Devulapalli Krishnaveni, Bhayal Amar Chand, Porike Shravan Kumar, Macherla Ramanna, Akka Jyothy, Nallari Pratibha, Ananthapur Venkateshwari

Abstract excerpt

BACKGROUND/AIMS: Gastric cancer (GC) is a multifactorial disorder mediated by genetic, epigenetic, and environmental risk factors. GC is the most common cancer in India and it is the third prominent cause of cancer death worldwide. A single nucleotide polymorphism (SNP) in the promoter region of interstitial collagenase (MMP-1) gene appears to have an impact on the transcriptional activity and regulation of its...

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Case-Control Studies
India
Matrix Metalloproteinase 1
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Stomach Neoplasms

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Identifiers

PMID: 25253367
DOI: 10.4103/1319-3767.141693
PMCID: PMC4196347

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