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Article

Relationships between ultrastructural scrapie pathology and patterns of abnormal prion protein accumulation.

Acta neuropathologica - 1 May 2004

Ersdal Cecilie, Simmons Marion M, González Lorenzo, Goodsir Caroline M, Martin Stuart, Jeffrey Martin

Abstract excerpt

On immunohistochemical examination several morphological types of disease-specific prion protein (PrP(d)) accumulation are recognised in the brain of sheep suffering from scrapie. The present study examined the relationship between the type of PrP(d) deposits seen by light microscopy and ultrastructural changes in the olivary nuclei and the dorsal motor nucleus of the vagus (DMNV) in naturally infected sheep with...

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Identifiers

PMID: 14986027
DOI: 10.1007/s00401-004-0830-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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