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Full sequencing analysis of estrogen receptor-alpha gene polymorphism and its association with breast cancer risk.

Anticancer research - 1 Jan 2000

Han Wonshik, Kang Daehee, Lee Kyung-Moo, Kim Hee Joung, Ahn Soo-Jung, Kim Seok Won, Chung Ki-Wook, Lee Eun Sook, Noh Dong-Young

Abstract excerpt

BACKGROUND: The estrogen receptor plays a critical role in breast cancer development and progression. So the genetic polymorphism of ER-alpha gene could affect cancer risk and phenotype. MATERIALS AND METHODS: We fully sequenced the ER-alpha gene to investigate its single nucleotide polymorphisms (SNPs) in 100 breast cancer patients and 100 controls. RESULTS: Six novel polymorphism in the control and 11 in cancer...

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PMID: 14981916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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