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Article

The Klebsiella pneumoniae O antigen contributes to bacteremia and lethality during murine pneumonia.

Infection and immunity - 1 Mar 2004

Shankar-Sinha Sunita, Valencia Gabriel A, Janes Brian K, Rosenberg Jessica K, Whitfield Chris, Bender Robert A, Standiford Ted J, Younger John G

Abstract excerpt

Bacterial surface carbohydrates are important pathogenic factors in gram-negative pneumonia infections. Among these factors, O antigen has been reported to protect pathogens against complement-mediated killing. To examine further the role of O antigen, we insertionally inactivated the gene encoding a galactosyltransferase necessary for serotype O1 O-antigen synthesis (wbbO) from Klebsiella pneumoniae 43816....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bronchoalveolar Lavage Fluid

Share to Complement C3

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Share to Mice, Inbred ICR

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Source

Open in PubMed Open full text

Identifiers

PMID: 14977947
DOI: 10.1128/IAI.72.3.1423-1430.2004
PMCID: PMC355988

Genes

CCL3
CXCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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