Article
Contribution of cell surface protein antigen PAc of Streptococcus mutans to bacteremia.
Microbes and infection - 1 Jan 2006
Nakano Kazuhiko, Tsuji Masato, Nishimura Kaoru, Nomura Ryota, Ooshima Takashi
Abstract excerpt
Streptococcus mutans, a major cariogenic bacterium, is occasionally isolated from the blood of patients with bacteremia and infective endocarditis. Mutant strains of S. mutans MT8148, defective in the major surface proteins glucosyltransferase (GTF) B-, C-, and D-, and protein antigen c (PAc), were constructed by insertional inactivation of each respective gene with an antibiotic resistant cassette....
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