Article
Lipopolysaccharide O1 antigen contributes to the virulence in Klebsiella pneumoniae causing pyogenic liver abscess.
PloS one - 1 Jan 2012
Hsieh Pei-Fang, Lin Tzu-Lung, Yang Feng-Ling, Wu Meng-Chuan, Pan Yi-Jiun, Wu Shih-Hsiung, Wang Jin-Town
Abstract excerpt
Klebsiella pneumoniae is the common cause of a global emerging infectious disease, community-acquired pyogenic liver abscess (PLA). Capsular polysaccharide (CPS) and lipopolysaccharide (LPS) are critical for this microorganism's ability to spread through the blood and to cause sepsis. While CPS t...
Topics
- Animals
- Antigens, Bacterial
- Bacterial Capsules
- Bacterial Proteins
- Base Sequence
- DNA Primers
- Genotype
- Immune Sera
- Immunoblotting
- Kaplan-Meier Estimate
- Klebsiella Infections
- Klebsiella pneumoniae
- Lipopolysaccharides
- Liver Abscess, Pyogenic
- Mice