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Article

Lipopolysaccharide O1 antigen contributes to the virulence in Klebsiella pneumoniae causing pyogenic liver abscess.

PloS one - 1 Jan 2012

Hsieh Pei-Fang, Lin Tzu-Lung, Yang Feng-Ling, Wu Meng-Chuan, Pan Yi-Jiun, Wu Shih-Hsiung, Wang Jin-Town

Abstract excerpt

Klebsiella pneumoniae is the common cause of a global emerging infectious disease, community-acquired pyogenic liver abscess (PLA). Capsular polysaccharide (CPS) and lipopolysaccharide (LPS) are critical for this microorganism's ability to spread through the blood and to cause sepsis. While CPS type K1 is an important virulence factor in K. pneumoniae causing PLA, the role of LPS in PLA is not clear. Here, we...

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PMID: 22427976
DOI: 10.1371/journal.pone.0033155
PMCID: PMC3299736

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