Article
Heterogeneous patterns of FLT3 Asp(835) mutations in relapsed de novo acute myeloid leukemia: a comparative analysis of 120 paired diagnostic and relapse bone marrow samples.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2004
Shih Lee-Yung, Huang Chein-Fuang, Wu Jin-Hou, Wang Po-Nan, Lin Tung-Liang, Dunn Po, Chou Meng-Chu, Kuo Ming-Chung, Tang Chung-Chih
Abstract excerpt
PURPOSE: We analyzed Asp(835) mutations of FLT3 on paired marrow samples at diagnosis and relapse from 120 adult patients with de novo acute myeloid leukemia (AML) to determine the role of FLT3 Asp(835) mutation in the relapse of AML. EXPERIMENTAL DESIGN: Asp(835) mutation was analyzed by DNA PCR...
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