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Article

SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests.

Genetic epidemiology - 1 Jul 2015

Li Jiang, Sham Pak Chung, Song Youqiang, Li Miaoxin

Abstract excerpt

Set-based association tests, combining a set of single-nucleotide polymorphisms into a unified test, have become important approaches to identify weak-effect or low-frequency risk loci of complex diseases. However, there is no comprehensive and user-friendly tool to estimate power of set-based tests for study design. We developed a simulation tool to estimate statistical power of multiple representative set-based...

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PMID: 25995121
DOI: 10.1002/gepi.21898

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