Article
Potent and selective inhibition of HIV and SIV by prostratin interacting with viral entry.
Antiviral chemistry & chemotherapy - 1 Nov 2003
Witvrouw Myriam, Pannecouque Christophe, Fikkert Valery, Hantson Anke, Van Remoortel Barbara, Hezareh Marjan, De Clercq Erik, Brown Stephen J
Abstract excerpt
Prostratin, a non-tumour promoting phorbol ester, exhibit a potent anti-HIV activity against human immunodeficiency virus type 1 (HIV-1). However, the antiviral mechanism of prostratin is not well defined. In the present study, we report that prostratin exhibits potent antiviral activity against...
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