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Article

Association study of Notch 4 polymorphisms with Alzheimer's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Mar 2004

Lambert J-C, Mann D, Harris J, Araria-Goumidi L, Chartier-Harlin M-C, Cottel D, Iwatsubo T, Amouyel P, Lendon C

Abstract excerpt

BACKGROUND: The NOTCH4 gene is located at 6p21.3, a site shown in several studies to have significant linkage with Alzheimer's disease. OBJECTIVE: To investigate the potential impact of two polymorphisms within this gene on the risk of developing Alzheimer's disease. METHODS: Genotyping of promot...

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Source

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Identifiers

PMID: 14966150
DOI: 10.1136/jnnp.2003.017368
PMCID: PMC1738953

Genes

NOTCH4
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14966150-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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