Article
Analysis of variance components in gene expression data.
Bioinformatics (Oxford, England) - 12 Jun 2004
Chen James J, Delongchamp Robert R, Tsai Chen-An, Hsueh Huey-miin, Sistare Frank, Thompson Karol L, Desai Varsha G, Fuscoe James C
Abstract excerpt
MOTIVATION: A microarray experiment is a multi-step process, and each step is a potential source of variation. There are two major sources of variation: biological variation and technical variation. This study presents a variance-components approach to investigating animal-to-animal, between-array, within-array and day-to-day variations for two data sets. The first data set involved estimation of technical...
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